Interferon Gamma Does Not Reverse Fibrosis in Hepatitis C Patients
with Advanced Liver Disease
"IFN-gamma-1b therapy was not able to reverse fibrosis in patients with advanced liver disease for 1 year," the authors concluded. "Subgroups of patients with elevated ITAC levels and perhaps less advanced disease may be considered for future studies with IFN-gamma-1b."
PJ Pockros, L Jeffers, N Afdhal, and others. Final results of a
double-blind, placebo-controlled trial of the antifibrotic efficacy of
interferon-gamma1b in chronic hepatitis C patients with advanced fibrosis or
cirrhosis. Hepatology 45(3): 569-578. March 2007.
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